Those who have stuck with Grey's Anatomy the last seven years have grown fond of Patrick Dempsey, but will soon have to learn to do without him. In his recent interview with Italian Vanity Fair, McDreamy confirms that the upcoming 8th season of Grey'swill be his last. While he calls the show a "great part" of his life and leaving "bittersweet," he reveals that he "can't see [himself] doing it anymore."

In truth, it revitalized his career, but he's right - it's time for him to move on.

So, that's one. IncludingEllen Pompeo, there are only four other original cast members remaining at Seattle Grace. As we recall, all of their contracts are up this season. Could we be seeing the last of Meredith & Cristina, Dr. Bailey and Alex as well? If they go, will the show last much longer anyway? And if they stay, but Patrick leaves, what will that mean for Meredith and Derek?!

So many questions that only Shonda Rhimes can answer!!! Dun, dun, dun!

What do U think?

TVline.com